Plikli SB 2020 - System comprises four plasma proteins, circulating as zymogens in the bloodstream https://plikli.xyz/story.php?title=system-comprises-four-plasma-proteins-circulating-as-zymogens-in-the-bloodstream-8 System comprises four plasma proteins, circulating as zymogens in the bloodstream or being assembled on various cell types: the serine proteases factor XII (FXII), factor XI (FXI), and prekallikrein (PKK) and the nonenzymatic cofactor high-molecularweight kininogen (HK). The latter forms equimolar complexes with plasma kallikrein (PK) or FXI. The cascade is initiated upon contact to a negatively c Mon, 22 Feb 2021 09:47:46 UTC en